Convergent synthesis of glycoalkaloids solasonine and its saponin derivative-Reference-Cited by-同舟云学术

Convergent synthesis of glycoalkaloids solasonine and its saponin derivative

Published:2024 Issue:72 Volume:60 Page:9753-9756
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yang Yue¹,Li Tong¹,Hao Huiran¹,Sheng Ju-Zheng¹²^ORCID,Li Tianlu¹²^ORCID,Peng Peng¹²^ORCID

Affiliation:

1. National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, 266237 Shandong, China

2. Key Laboratory of Chemical Biology, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan, 250012 Shandong, China

Abstract

Efficient and convergent synthesis of glycoalkaloids solasonine and its saponin derivative was achieved via a novel AuCl3–tBuCN cooperative catalysis 1,2-trans glycosidation strategy.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC01850H

Reference54 articles.

1. Developmental Toxicology of Solamargine and Solasonine Glycoalkaloids in Frog Embryos

2. Leptine Glycoalkaloids Reduce Feeding by Colorado Potato Beetle in Diploid Solanum sp. Hybrids

3. Synergism between the potato glycoalkaloids α-chaconine and α-solanine in inhibition of snail feeding

4. Glycoalkaloids and Metabolites Inhibit the Growth of Human Colon (HT29) and Liver (HepG2) Cancer Cells

5. Solasodine-3- O -β- d -glucopyranoside kills Candida albicans by disrupting the intracellular vacuole