Novel insights into the effect of folate–albumin binding on the transport of ascorbic acid as an anticancer agent: chemometric analysis based on combined spectroscopic and electrochemical studies
Author:
Affiliation:
1. Department of Chemistry
2. Faculty of Science
3. Yazd University
4. Yazd 89195-741
5. Iran
6. Laboratory of Bioinformatics and Drug Design
7. Institute of Biochemistry and Biophysics
8. University of Tehran
9. Tehran
Abstract
The electrochemical behavior of ascorbic acid and folic acid upon their interaction with albumin is investigated using electrochemical, chemometric and docking studies.
Funder
Yazd University
University of Tehran
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ01572D
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1. Catalytic Therapy of Cancer with Ascorbate and Extracts of Medicinal Herbs
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4. Ascorbic acid and its pro-oxidant activity as a therapy for tumours of oral cavity – A systematic review
5. Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
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