A metal-free tandem dehydrogenative α-arylation reaction of propargylic alcohols with 2-alkynylbenzaldoximes toward the synthesis of α-(4-bromo-isoquinolin-1-yl)-propenone skeletons-Reference-Cited by-同舟云学术

A metal-free tandem dehydrogenative α-arylation reaction of propargylic alcohols with 2-alkynylbenzaldoximes toward the synthesis of α-(4-bromo-isoquinolin-1-yl)-propenone skeletons

Published:2022 Issue:3 Volume:20 Page:579-583
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Alatat Khalil¹,Abbasi Kejani Alireza¹^ORCID,Nikbakht Ali¹,Bijanzadeh Hamid Reza²,Balalaie Saeed¹³^ORCID

Affiliation:

1. Peptide Chemistry Research Institute, K. N. Toosi University of Technology, P. O. Box 15875-4416, Tehran, Iran

2. Department of Environmental Sciences, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, Tehran, Iran

3. Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Abstract

Synthesis of functionalized propenones is introduced through a tandem dehydrogenative α-arylation reaction of 2-alkynylbenzaldoximes with propargylic alcohols under metal-free conditions.

Funder

Alexander von Humboldt-Stiftung

Iran National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D1OB02114A

Reference67 articles.

1. Total Synthesis of Two 8-Oxoprotoberberine Alkaloids: Alangiumkaloids A and B

2. New mechanistic interpretations for nitrone reactivity

3. Synthesis and Transformations of Nitrones for Organic Synthesis

4. 2-Alkynylbenzaldoxime: a versatile building block for the generation of N-heterocycles

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