Chemoenzymatic one-pot reaction from carboxylic acid to nitrile via oxime-Reference-Cited by-同舟云学术

Chemoenzymatic one-pot reaction from carboxylic acid to nitrile via oxime

Published:2022 Issue:1 Volume:12 Page:62-66
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Horvat Melissa¹,Weilch Victoria¹,Rädisch Robert²³^ORCID,Hecko Sebastian⁴,Schiefer Astrid⁴,Rudroff Florian⁴^ORCID,Wilding Birgit⁵⁶^ORCID,Klempier Norbert⁶,Pátek Miroslav²,Martínková Ludmila²,Winkler Margit¹⁵^ORCID

Affiliation:

1. Institute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, A-8010 Graz, Austria

2. Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, CZ-142 20 Prague, Czech Republic

3. Department of Genetics and Microbiology, Faculty of Science, Charles University, Viničná 5, CZ-12844 Prague 2, Czech Republic

4. Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/OC-163, A-1060 Vienna, Austria

5. Acib GmbH, Krenngasse 37, A-8010 Graz, Austria

6. Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria

Abstract

We report a new chemoenzymatic cascade starting with aldehyde synthesis by carboxylic acid reductase (CAR) followed by chemical in situ oxime formation and enzymatic dehydration by aldoxime dehydratase (Oxd).

Funder

Austrian Science Fund

Grantová Agentura České Republiky

Österreichische Forschungsförderungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CY/D1CY01694F

Reference39 articles.

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