A mechanically robust and stable estradiol-loaded PHEMA-based hydrogel barrier for intrauterine adhesion treatment-Reference-Cited by-同舟云学术

A mechanically robust and stable estradiol-loaded PHEMA-based hydrogel barrier for intrauterine adhesion treatment

Published:2022 Issue:42 Volume:10 Page:8684-8695
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Xie Xiangyan¹,Xu Ruijuan²,Ouyang Hongyan¹,Tan Shiqiao²,Guo Chuan³,Luo Xingqi¹,Xie Yuanjie¹,Wu Di¹,Dong Xiangyu⁴,Wu Jinrong⁴^ORCID,Wang Yi¹⁴^ORCID,Zhao Lijuan¹

Affiliation:

1. College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 60068, China

2. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China

3. Orthopedic research institute, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, China

4. State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China

Abstract

The mechanically robust estradiol-loaded PHMH-Si hydrogel could not only release estradiol sustainably and locally but also be a mechanically robust and stable barrier in the uterine cavity, which may be a novel and effective treatment for IUAs.

Funder

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01740G

Reference37 articles.

1. Mini-Review of the New Therapeutic Possibilities in Asherman Syndrome—Where Are We after One Hundred and Twenty-Six Years?