Dependence of gold nanoparticle radiosensitization on cell geometry

Author:

Sung Wonmo12345ORCID,Ye Sung-Joon56789,McNamara Aimee L.123410,McMahon Stephen J.11121314ORCID,Hainfeld James154,Shin Jungwook123410,Smilowitz Henry M.16174,Paganetti Harald123410,Schuemann Jan123410ORCID

Affiliation:

1. Department of Radiation Oncology

2. Massachusetts General Hospital

3. Boston

4. USA

5. Program in Biomedical Radiation Sciences

6. Department of Transdisciplinary Studies

7. Graduate School of Convergence Science and Technology

8. Seoul National University

9. Seoul

10. Harvard Medical School

11. Centre for Cancer Research and Cell Biology

12. Queen's University Belfast

13. Belfast

14. UK

15. Nanoprobes Inc. Yaphank

16. UConn Health

17. Connecticut

Abstract

Detailed modeling of cell geometries was shown to be important to estimate radiosensitization effects of gold nanoparticles (GNPs).

Funder

Seoul National University

National Cancer Institute

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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