·YlideFluor-CF2Cl: a shelf-stable, versatile electrophilic or radical chlorodifluoromethylating reagent-Reference-Cited by-同舟云学术

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·YlideFluor-CF2Cl: a shelf-stable, versatile electrophilic or radical chlorodifluoromethylating reagent

Published:2024 Issue:14 Volume:11 Page:3924-3928
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Tian¹,Zhang Yuhan¹,Li Zimeng²^ORCID,Wu Botao²,Shen Qilong¹²^ORCID

Affiliation:

1. Henan Institute of Advanced Technology, Zhengzhou University, 97 Wenhua Lu, Zhengzhou, Henan Province, 450003, PR China

2. Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, PR China

Abstract

An easily available chlorodifluoromethylating reagent YlideFluor-CF2Cl based on the sulfonium ylide skeleton was developed.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00600C

Reference37 articles.

1. Highlights on U.S. FDA-approved fluorinated drugs over the past five years (2018–2022)

2. Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties

3. Aromatic Trifluoromethylation with Metal Complexes

4. Progress in Copper-Mediated Formation of Trifluoromethylated Arenes

5. Introduction of Fluorine and Fluorine-Containing Functional Groups

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