Partial thermal imidization of polyelectrolyte multilayer cell tethering surfaces (TetherChip) enables efficient cell capture and microtentacle fixation for circulating tumor cell analysis-Reference-Cited by-同舟云学术

Partial thermal imidization of polyelectrolyte multilayer cell tethering surfaces (TetherChip) enables efficient cell capture and microtentacle fixation for circulating tumor cell analysis

Published:2020 Issue:16 Volume:20 Page:2872-2888
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ju Julia A.¹²³⁴^ORCID,Lee Cornell J.¹²³⁴,Thompson Keyata N.¹²³⁴,Ory Eleanor C.¹²³⁴,Lee Rachel M.¹²³⁴^ORCID,Mathias Trevor J.¹²³⁴⁵^ORCID,Pratt Stephen J. P.¹²³⁴⁶,Vitolo Michele I.¹²³⁴⁵^ORCID,Jewell Christopher M.⁷⁸⁴⁹¹⁰^ORCID,Martin Stuart S.¹²³⁴⁵

Affiliation:

1. Marlene and Stewart Greenebaum NCI Comprehensive Cancer Center

2. University of Maryland School of Medicine

3. Baltimore

4. USA

5. Graduate Program in Molecular Medicine

6. Department of Biochemistry and Molecular Biology

7. Fischell Department of Bioengineering

8. University of Maryland

9. United States Department of Veterans Affairs

10. VA Maryland Health Care System

Abstract

TetherChip is an optimized nanosurface comprised of a polyelectrolyte multilayer and a terminal lipid layer in a microfluidics system to enable the study of non-adherent tumor cell behaviors that are relevant to cancer metastasis.

Funder

U.S. Department of Veterans Affairs

National Institutes of Health

American Cancer Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00207K

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1. A Perspective on Cancer Cell Metastasis