Sunflower pollen-derived microcapsules adsorb light and bacteria for enhanced antimicrobial photothermal therapy

Author:

Yang Yao1,Wang Bin12,Liu Qian3ORCID,Wei Zhenghua12,Mou Ziye4,Li Quan14,Chen Chunfa12ORCID,You Zaichun4,Li Bang Lin5ORCID,Wang Guansong12ORCID,Xu Zhi126,Qian Hang126ORCID

Affiliation:

1. Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, 183 Xinqiao Street, Chongqing 400037, China

2. Chongqing Key Laboratory of Precision Medicine and Prevention of Major Respiratory Diseases, Chongqing 400037, China

3. Laboratory of Pharmacy and Chemistry, and Laboratory of Tissue and Cell Biology, Lab Teaching & Management Center, Chongqing Medical University, Chongqing 400016, China

4. Department of General Practice, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China

5. School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China

6. Yu-Yue Pathology Scientific Research Center, Chongqing, China

Abstract

In this study, we report that natural sunflower sporopollenin-based microcapsules (HSECs) and curdlan suspension capture bacteria locally and form hydrogels on wounds upon NIR light stimulation, showing superior wound healing results in both in vitro and in vivo.

Funder

National Natural Science Foundation of China

Army Medical University

Publisher

Royal Society of Chemistry (RSC)

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