Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin-Reference-Cited by-同舟云学术

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

Published:2021 Issue:35 Volume:9 Page:7145-7166
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Ndayishimiye John¹^ORCID,Cao Yuxue¹,Kumeria Tushar²^ORCID,Blaskovich Mark A. T.³^ORCID,Falconer James Robert¹,Popat Amirali¹⁴^ORCID

Affiliation:

1. School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Brisbane, Queensland 4102, Australia

2. School of Materials Science and Engineering, University of New South Wales, New South Wales, Australia

3. Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia

4. Mater Research Institute – The University of Queensland, Translational Research Institute, 37 Kent St, Woolloongabba, QLD 4102, Australia

Abstract

Vancomycin (Van) is an antibiotic of choice for many drug resistant infections but cannot be given orally due to its poor permeability. Encapsulation of Vancomycin within MSNs improved its gastrointestinal permeation and provided controlled release.

Funder

National Health and Medical Research Council

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01430G

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