A siRNA-induced peptide co-assembly system as a peptide-based siRNA nanocarrier for cancer therapy-Reference-Cited by-同舟云学术

A siRNA-induced peptide co-assembly system as a peptide-based siRNA nanocarrier for cancer therapy

Published:2018 Issue:4 Volume:5 Page:745-752
ISSN:2051-6347
Container-title:Materials Horizons
language:en
Short-container-title:Mater. Horiz.

Author:

Li Wenjun¹²³⁴⁵,Wang Dongyuan¹²³⁴⁵,Shi Xiaodong¹²³⁴⁵,Li Jingxu¹²³⁴⁵,Ma Yue¹²³⁴⁵,Wang Yanding¹²³⁴⁵,Li Tingting⁶³⁴⁵,Zhang Jianing¹²³⁴⁵,Zhao Rongtong¹²³⁴⁵,Yu Zhiqiang⁷⁸⁹¹⁰⁵^ORCID,Yin Feng¹²³⁴⁵^ORCID,Li Zigang¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics

2. School of Chemical Biology and Biotechnology

3. Peking University Shenzhen Graduate School

4. Shenzhen

5. China

6. School of Advanced Material

7. School of Pharmaceutical Sciences

8. Guangdong Provincial Key Laboratory of New Drug Screening

9. Southern Medical University

10. Guangzhou 510515

Abstract

Herein, we report a unique siRNA-induced peptide co-assembly nanocarrier, which could efficiently co-assemble upon the addition of siRNA, forming nanospheres with high biocompatibility and transfection efficiency bothin vitroandin vivo.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MH/C8MH00392K

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