A novel chitosan–PEG hydrogel embedded with in situ silver nanoparticles of Clerodendrum glandulosum Lindl. extract: evaluation of its in vivo diabetic wound healing properties using an image-guided machine learning model

Author:

Majie Ankit1,Saha Rajdeep1,Sarkar Arnab2ORCID,Bhowmik Rudranil2,Karmakar Sanmoy2,Sharma Vishal3,Deokar Kaushal3,Haque Asad ul3,Tripathy Sanjaya Shankar3,Sarkar Biswatrish1ORCID

Affiliation:

1. Group Polyphenol-BIT, Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, India, 835215

2. Bioequivalence Study Centre, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India

3. Department of Electronics and Communication Engineering, Birla Institute of Technology, Mesra, Ranchi, India, 835215

Abstract

Clerodendrum glandulosum extract reduced silver nanoparticles were prepared by in situ technique within chitosan-PEG hydrogel matrix and characterized for its in vitro and in vivo diabetic wound healing activities.

Funder

All India Council for Technical Education

Indian Council of Medical Research

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

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