Design and synthesis of amino acid derivatives of substituted benzimidazoles and pyrazoles as Sirt1 inhibitors-Reference-Cited by-同舟云学术

Design and synthesis of amino acid derivatives of substituted benzimidazoles and pyrazoles as Sirt1 inhibitors

Published:2022 Issue:7 Volume:12 Page:3809-3827
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Purushotham Nikil¹,Singh Mrityunjay²³^ORCID,Paramesha Bugga²,Kumar Vasantha¹^ORCID,Wakode Sharad³,Banerjee Sanjay K.²,Poojary Boja¹,Asthana Shailendra²^ORCID

Affiliation:

1. Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka-574 199, India

2. Translational Health Science and Technology Institute (THSTI), NCR Biotech Science Cluster, Faridabad, Haryana-121001, India

3. Delhi Institute of Pharmaceutical Sciences and Research, DPSR University, M.B Road, Pushp Vihar, Sector 3, New Delhi 110017, India

Abstract

Owing to its presence in several biological processes, Sirt1 acts as a potential therapeutic target for many diseases.

Funder

Council of Scientific and Industrial Research, India

Translational Health Science and Technology Institute

Department of Science and Technology, Ministry of Science and Technology, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA06149F

Reference78 articles.

1. Sirtuins 1 and 2 Are Universal Histone Deacetylases

2. Sirtuins in mammals: insights into their biological function

3. The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer

4. Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism

5. Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins

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