Neuroinflammatory inhibitors from Gardneria nutans Siebold & Zuccarini

Author:

Si Ying-Ying12ORCID,Wang Wei-Wei1,Feng Qing-Mei1,Zhao Zhen-Zhu12ORCID,Xue Gui-Min12,Sun Yan-Jun12,Feng Wei-Sheng12ORCID,Young Jun-Im3,Wang Xian-Shi134

Affiliation:

1. College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China

2. The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China

3. College of Pharmacy, Chonnam National University, Gwangju 500-757 61186, South Korea

4. School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China

Abstract

Four new compounds were isolated from G. nutans. Compounds 1–2 are two rare monoterpene indole alkaloids with the glucosyl moiety located at C-12 and represent the first two examples of enantiomer of ajmaline type monoterpene indole alkaloids.

Funder

Henan University of Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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