Investigation of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents: novel Akt/PKB signaling pathway inhibitors-Reference-Cited by-同舟云学术

Investigation of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents: novel Akt/PKB signaling pathway inhibitors

Published:2016 Issue:4 Volume:7 Page:646-653
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Nagarsenkar Atulya¹²³⁴,Prajapti Santosh Kumar¹²³⁴,Guggilapu Sravanthi Devi¹²³⁴,Birineni Swetha⁵⁶⁷⁴,Sravanti Kotapalli Sudha⁵⁶⁷⁴,Ummanni Ramesh⁵⁶⁷⁴,Babu Bathini Nagendra¹²³⁴

Affiliation:

1. Department of Medicinal Chemistry

2. National Institute of Pharmaceutical Education and Research

3. Hyderabad

4. India

5. Center for Chemical Biology

6. Indian Institute of Chemical Technology (CSIR-IICT)

7. Hyderabad 500007

Abstract

Novel triazole-linked indole and oxindole glycoconjugates as inhibitors of the Akt/PKB signaling pathway.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00513B

Reference38 articles.

1. The Akt/PKB pathway: molecular target for cancer drug discovery

2. Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells

3. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

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