Thermodynamics of cell-penetrating HIV1 TAT peptide insertion into PC/PS/CHOL model bilayers through transmembrane pores: the roles of cholesterol and anionic lipids
Author:
Affiliation:
1. Merck Research Laboratories
2. New Jersey 07033, USA
3. Department of Chemistry and Biochemistry
4. University of Delaware
5. Newark, USA
Abstract
Coarse-grain molecular simulations explore thermodynamics of HIV1-TAT permeation into mixed model bilayers of varying concentrations and cholesterol content. The role and nature of transmembrane pores are investigated.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/SM/C5SM01696G
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