Diosgenin relieves oxaliplatin-induced pain by affecting TLR4/NF-κB inflammatory signaling and the gut microbiota-Reference-Cited by-同舟云学术

Diosgenin relieves oxaliplatin-induced pain by affecting TLR4/NF-κB inflammatory signaling and the gut microbiota

Published:2023 Issue:1 Volume:14 Page:516-524
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Man Shuli¹^ORCID,Xie Lu¹,Liu Xuanshuo¹,Wang Genbei²,Liu Changxiao³,Gao Wenyuan⁴^ORCID

Affiliation:

1. State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, National and Local United Engineering Lab of Metabolic Control Fermentation Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China

2. State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tasly Holding Group Co., Ltd, Tianjin 300410, China

3. State Key Laboratory of Drug Release Technology and Pharmacokinetics. Tianjin Institute of Pharmaceutical Research Co., Ltd, Tianjin 300462, China

4. Tianjin Key Laboratory for Modern Drug Delivery and High Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China

Abstract

Diosgenin extracted from fenugreek, yam and other foods exhibits a wide range of pharmacological activities, especially for the treatment of pain and other nervous system diseases.

Funder

Tianjin University of Science and Technology

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO02877H

Reference41 articles.

1. Mechanisms of Chemotherapy-Induced Peripheral Neuropathy

2. Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential