DNA intercalators as amyloid assembly modulators: mechanistic insights
Author:
Affiliation:
1. Kusuma School of Biological Sciences
2. Indian Institute of Technology Delhi
3. New Delhi
4. India
Abstract
DNA intercalators modulate amyloid assembly of proteins through specific hetero-aromatic interactions diverting them to form amorphous aggregates.
Funder
Indian Council of Medical Research
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA26313E
Reference74 articles.
1. The Alzheimer's Amyloid-β(1–42) Peptide Forms Off-Pathway Oligomers and Fibrils That Are Distinguished Structurally by Intermolecular Organization
2. Sporadic Creutzfeldt-Jakob disease with focal findings: caveats to current diagnostic criteria
3. Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures
4. Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
5. Protein Misfolding, Functional Amyloid, and Human Disease
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