Mechanistic aspects of thioflavin-T self-aggregation and DNA binding: evidence for dimer attack on DNA grooves-Reference-Cited by-同舟云学术

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Mechanistic aspects of thioflavin-T self-aggregation and DNA binding: evidence for dimer attack on DNA grooves

Published:2014 Issue:37 Volume:16 Page:20061-20072
ISSN:1463-9076
Container-title:Phys. Chem. Chem. Phys.
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Biancardi A.¹²³^ORCID,Biver T.¹²³,Burgalassi A.¹²³,Mattonai M.¹²³,Secco F.¹²³,Venturini M.¹²³

Affiliation:

1. Department of Chemistry and Industrial Chemistry

2. University of Pisa

3. 56126 Pisa, Italy

Abstract

Simultaneous intercalation and groove-binding is infrequent: here, under dye excess, the TFT dimer binds to grooves of TFT-intercalated DNA.

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CP/C4CP02838D

Reference60 articles.

1. Fluorescence Quantum Yield of Thioflavin T in Rigid Isotropic Solution and Incorporated into the Amyloid Fibrils

2. Molecular Rotors: What Lies Behind the High Sensitivity of the Thioflavin-T Fluorescent Marker

3. Computational Study of Thioflavin T Torsional Relaxation in the Excited State

4. The incidence of cerebral amyloid angiopathy in Alzheimer's disease

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