Engineering of pH-triggered nanoplatforms based on novel poly(2-methyl-2-oxazoline)-b-poly[2-(diisopropylamino)ethyl methacrylate] diblock copolymers with tunable morphologies for biomedical applications

Author:

Černoch Peter1234,Jager Alessandro1234,Černochová Zulfiya1234,Sincari Vladimir1234,Albuquerque Lindomar J. C.5678,Konefal Rafal1234ORCID,Pavlova Ewa1234,Giacomelli Fernando C.5678ORCID,Jager Eliezer1234ORCID

Affiliation:

1. Institute of Macromolecular Chemistry

2. Czech Academy of Sciences

3. 16206 Prague

4. Czech Republic

5. Centro de Ciências Naturais e Humanas

6. Universidade Federal do ABC

7. Santo André 09210-580

8. Brazil

Abstract

CROP and RAFT polymerization was used to produce PMeOxm-b-PDPAn block copolymers. The microfluid technique enabled the manufacturing of pH-triggered nanoplatforms with different morphologies as driven by the overall molecular weight of the chains.

Funder

Grantová Agentura České Republiky

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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