Macromolecular crystallography beamlines at the Canadian Light Source: building on success

Author:

Fodje MichelORCID,Mundboth Kiran,Labiuk Shaunivan,Janzen Kathryn,Gorin James,Spasyuk Denis,Colville Scott,Grochulski Pawel

Abstract

The Canadian Macromolecular Crystallography Facility (CMCF) consists of two beamlines dedicated to macromolecular crystallography: CMCF-ID and CMCF-BM. After the first experiments were conducted in 2006, the facility has seen a sharp increase in usage and has produced a significant amount of data for the Canadian crystallographic community. Upgrades aimed at increasing throughput and flux to support the next generation of more demanding experiments are currently under way or have recently been completed. At CMCF-BM, this includes an enhanced monochromator, automounter software upgrades and a much faster detector. CMCF-ID will receive a major upgrade including a new undulator, a new monochromator and new optics to stably focus the beam onto a smaller sample size, as well as a brand-new detector.

Funder

Canada Foundation for Innovation

Natural Sciences and Engineering Research Council of Canada

National Research Council Canada

Canadian Institutes of Health Research

Government of Saskatchewan

University of Saskatchewan

Publisher

International Union of Crystallography (IUCr)

Subject

Structural Biology

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