Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone

Abstract

The title compound, C13H14NO2F3, crystallises with two molecules,AandB, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76 (2) and 75.23 (2)° in moleculesAandB, respectively. The bond-angle sums around the N atoms [359.1 and 359.7° for moleculesAandB, respectively] indicatesp2hybridization for these atoms. In the crystal, O—H...O hydrogen bonds link the molecules into separate [100] chains ofAandBmolecules. The chains are cross-linked by C—H...O interactions, generating alternating (001) sheets ofAandBmolecules.