Opioids Potentially Exacerbate Ischemic Spinal Cord Injury

Author:

KAKINOHANA Manabu,ISEKI Satoshi,NAKAMURA Seiya,FUCHIGAMI Tatsuya,KAMIZATO Kota,SUGAHARA Kazuhiro

Publisher

Japan Society for Clinical Anesthesia

Reference19 articles.

1. 1) Kakinohana M, Marsala M, Carter C, et al.: Neuraxial morphine may trigger transient motor dysfunction after a noninjurious interval of spinal cord ischemia: a clinical and experimental study. Anesthesiology 98: 862-870, 2003

2. 2) Baskin DS, Hosobuchi Y: Naloxone reversal of ischaemic neurological deficits in man. Lancet 2: 272-275, 1981

3. 3) Baskin DS, Kieck CF, Hosobuchi Y: Naloxone reversal and morphine exacerbation of neurologic deficits secondary to focal cerebral ischemia in baboons. Brain Res 290: 289-296, 1984

4. 4) Kofke WA, Garman RH, Garman R, et al.: Opioid neurotoxicity: fentanyl-induced exacerbation of cerebral ischemia in rats. Brain Res 818: 326-334, 1999

5. 5) Fuchigami T, Taira Y, Kakinohana M, et al.: Repetitive intrathecal administration of morphine induces irreversible paraplegia after non-injurious interval of spinal cord ischemia in the rat. Biologia 54: 51-60, 1999

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