Analysis of Human Genes Associated with Ebola using Online Bioinformatics Tools

Abstract

Ebola is a deadlydisease caused by a virus in the family of Filoviridae. The virion is a single-stranded RNA of negative polarity and proteins enclosed in a lipid membrane. This ebolavirus species in African countries has caused several severe epidemics. Its infection causes a rapidly fatal hemorrhagic fever in humans for which no approved antivirals are available. Currently, the diagnostic tests for this deadly disease are Enzyme-Linked Immunoassay (ELISA) and Polymerase Chain Reaction (PCR) tests; viral cultivation and biopsy samples may also be used. So, there is no standard treatment for Ebola hemorrhagic fever and only supportive therapy, and experimental treatment is available. We used online bioinformatics tools to understand and look for new therapeutic targets.