Clinical case of a patient with subungual melanoma

Author:

Pavlov Yu. I.1,Volkov V. V.2,Gromov I. A.1,Kholopov A. A.1ORCID

Affiliation:

1. South Ural State Medical University

2. Clinical Hospital No. 8

Abstract

Subungual melanoma is a rare malignant tumor, little known to practitioners. Its location makes diagnosis difficult and requires differentiation with conditions such as onychomycosis, panaritium, hematoma, etc. Unsymptomatic onset brings more problems, the error level during visual examination even among experienced oncologists reaches 25–40%, and the average life expectancy of patients with fully manifested melanoma is limited to 3–4 years.So we present a clinical case to emphasize the need for oncological alertness during an outpatient examination of the subungual lesions. A 32-year-old woman came to the reception complaining of a non-healing bleeding, relatively painless wound of the left little toe. The condition was associated with trauma, for about a month she treated the wound herself, “cauterizing” it with antiseptics.After outpatient treatment of a granulating wound, the material was sent for histological diagnosis, which showed the presence of pigmentless melanoma in the stage of active growth. The woman was urgently hospitalized in the oncology department, where 5th finger exarticulation and inguinal-iliac lymphadenectomy were performed successfully. After this, the condition remained stable, but 14 months later there was a formation in the area of the postoperative scar. A study of a new surgical material confirmed the recurrence of malignant melanoma with Clark invasion level 2.In our opinion, outpatient surgeons should not delay histological examination for all ulcerative and granulomatous lesions of the feet, which will improve the differential diagnosis.

Publisher

Remedium, Ltd.

Reference8 articles.

1. Davydov M.I., Aksel E.M. Statistics of malignant neoplasms in Russia and the CIS countries in 2007. Vestnik RONTs im. N.N. Blokhina = Journal of N.N. Blokhin RCRC. 2009;20(3):52–90. (In Russ.) Available at: https://cyberleninka.ru/article/n/zabolevaemost-zlokachestvennymi-novoobrazovaniyaminaseleniya-rossii-i-stran-sng-v-2007-g/viewer.

2. Chissov V.I., Starinskiy V.V., Petrova G.V. (eds.). Malignant neoplasms in Russia in 2011 (morbidity and mortality). Moscow: National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; 2013. 289 p. (In Russ.) Available at: https://oncology-association.ru/files/medstat/2011.pdf.

3. Aksel E.M., Davydov M.I. Mortality of the population of Russia and the CIS countries from malignant neoplasms in 2008. Vestnik RONTs im. N.N. Blokhina = Journal of N.N. Blokhin RCRC. 2011;22(3S1):93–123. (In Russ.) Available at: https://elibrary.ru/item.asp?id=17334089.

4. Markovic S.N., Erickson L.A., Ravi D. Rao, Weenig R.H., Pockaj B.A., Bardia A. et al. Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention and Diagnosis. Mayo Clin Proc. 2007;82(3):364–380. doi: 10.4065/82.3.364.

5. Yatsenko S.K. Epidemiology of Malignant Melanoma in the Republic of Tajikistan. Voprosy onkologii = Oncology issues. 2006;52(1):95–97. (In Russ.) Available at: https://elibrary.ru/item.asp?id=12880757.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Melanoma and basal cell skin cancer in a patient with HIV infection. Clinical observation;HIV Infection and Immunosuppressive Disorders;2024-04-18

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3