Personalization of the use of non-steroidal anti-inflammatory drugs for musculoskeletal diseases. Resolution on the results of the Meeting of Experts of December 13, 2017

Author:

Karateev A. E.1,Lila A. M.1,Dydykina I. S.1,Kamchatnov P. R.2,Mazurenko S. O.3,Naprienko M. V.4,Novikova D. S.1,Ostroverkhov O. P.5,Pchelintsev M. V.6

Affiliation:

1. Nasonova Research Institute of Reumatology

2. Pirogov Russian National Research Medical Ministry of Health of Russia

3. St. Petersburg State University

4. Sechenov First Moscow State Medical University

5. Astrakhan State Medical University

6. Pavlov First Saint Petersburg State Medical University

Abstract

The personalization of therapy is one of the innovative approaches gaining an increasingly strong foothold in modern medicine, implying an individual approach to each patient, taking into account the individual characteristics of the patient and the specific clinical case. This same standpoint of personified therapy should be used to plan rational analgesic therapy, the most important component of managing patients with the most common and socially significant diseases, with conditions that have a significant impact on the patient’s quality of life and worsen the course of concomitant diseases. The Meeting of Experts of different specialties such as rheumatologists, neurologists, cardiologists and clinical pharmacologists considered the key aspects of the prescription of NSAIDs, the most widely used class of painkillers, including those used for the relief of musculoskeletal pain. It was noted that when choosing NSAIDs, the practitioner should take into account the diagnosis, the planned duration of  analgesic therapy, the intensity of pain, medical history data, the presence of comorbid diseases and risk factors for drug complications. There are different types of NSAIDs, some of which are most useful for urgent acute pain therapy (eg, ketoprofen), while others are most suitable for long-term pain management in chronic diseases (eg, etoricoxib). In any case, the practitioner should take into account the priority of patient safety and pay the utmost attention to the prevention of NSAIDassociated complications, and also keep in mind the duration of the specific drug administration permitted by the patient information leaflet. It was also noted that the launch of a new generic etoricoxib (Kostarox®) expands the possibilities of analgesic therapy for the Russian practitioners.

Publisher

Remedium, Ltd.

Subject

General Medicine

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