Individually orientated choice of mucolytic drug for coughing in a child with acute respiratory viral infections

Author:

Melnikova I. M.1,Minernitsky Yu. L.2

Affiliation:

1. Federal State Budgetary Educational Institution of Higher Education «Yaroslavl State Medical University» of the Ministry of Health of the Russian Federation

2. Separate business unit «Research Clinical Institute of Pediatrics named after Academician Yu.E. Veltischev» of the Federal State Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov « of the Ministry of Health of the Russian Federation

Abstract

Coughing in acute respiratory infections, regardless of the level of infection: upper or lower respiratory tract is a frequent clinical symptom in childhood. The analysis of the modern literature and the data of the authors’ own researches testify to the fact that the prescription of mucoactive therapy in a complex of therapeutic measures (etiotropic, basic therapy, bronchopulmonary drainage, etc.).) should be differentiated and determined not only by the nature and severity of coughs, separated sputum, but also by individual characteristics of the patient, the severity and course of bronchopulmonary pathology, the age of the child, the presence of adverse environmental factors (in particular, passive smoking), the level of compliance with the patient. The use of combined medications simultaneously influencing various pathogenetic mechanisms of inflammation and coughing becomes a promising direction of mucoactive therapy. One of them is Eucabal® syrup containing liquid extracts of thyme and plantain. Due to the synergy of its components, Eucabal® syrup has an expectorant and anti-inflammatory effect, which is important in the initial period of acute respiratory viral infections (tracheitis, bronchitis tracheobronchitis), especially in dry, painful cough with hard-to-remove sputum. In case of acute respiratory viral infections accompanied by a wet cough with a viscous, difficult to separate sputum, mucolytic agents are shown first of all. One of the modern widely used drugs of this group is acetylcysteine (ESPA-NAC®) in a convenient dosage form.

Publisher

Remedium, Ltd.

Subject

General Medicine

Reference52 articles.

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2. Bilichenko T.N., Chuchalin A.G. Morbidity and mortality of the Russian population from acute respiratory viral infections, pneumonia and vaccine prophylaxis. Therapeutic archive [Terapevticheskiy arkhiv]. 2018;01:22-26. (In Russ).

3. Zaitsev A.A. Coughing: Protusive therapy in focus. RMJ. 20184;26:10-1, 22-25. (In Russ).

4. Mizernitskiy Yu.L. Expectorant and mucolytic agents in therapy of bronchopulmonary diseases in children. Guidance on pharmacotherapy in pediatrics and pediatric surgery (under the editorship of A.D. Tsaregorodtseva, V.A. Tabolina). T.1 Pharmacotherapy in pediatric pulmonology (edited by S.Yu. Kaganova). Moscow: Medpraktika-M, 2002:123-140. (In Russ).

5. Rozinova N.N., Mizernitsky Yu.L. Chronic lung diseases in children. M: Practice, 2011. 234 с.

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