Role of combined mucolytic therapy in infectious and inflammatory diseases of the respiratory system in children

Author:

Mizernitsky Yu. L.1,Melnikova I. M.2

Affiliation:

1. Research Clinical Institute of Pediatrics named after Academician Yu.E. Veltischev of the Federal State Educational Institution of Higher Education Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation

2. Federal State Budgetary Educational Institution of Higher Education Yaroslavl State Medical University of the Ministry of Health of the Russian Federation

Abstract

The use of combined medicines simultaneously influencing various pathogenetic mechanisms of inflammation and coughing becomes an essential direction of mucoactive therapy in childhood. One of these is thiamphenicol glycinate acetylcysteinate, which has both mucolytic and antibacterial effects, which significantly expands the possibilities of therapy in bacterial etiology of acute and exacerbation of chronic respiratory diseases, increases the effectiveness of therapeutic measures, improves compliance.

Publisher

Remedium, Ltd.

Subject

General Medicine

Reference33 articles.

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2. Zhakov Ya.I., Minina E.E., Babaylov M.S. Influence of lazolvan (ambroxol) on the dynamics of inflammatory process of bronchial mucosa after acute bronchitis in children according to induced sputum. RMZh. 2011;19(22):1361-1364. (In Russ.)

3. Kunelskaya N.L., Turovsky A.B., Izotova G.N. et al. Possibilities of inhalation application of combined preparations in treatment of acute sinusitis. Med. sovet. 2014;3:30-33. (In Russ.)

4. Melnikova I.M., Mizernitsky Yu.L., Batozhargalova B.C., Loginevskaya Ya.V. Modern principles of mucolytic therapy in children with acute and chronic bronchopulmonary diseases. Ros. vestn. perinatol. i pediatrii. 2011;56(2):4550. (In Russ.)

5. Melnikova I.M., Udaltsova E.V., Mizernitsky Yu.L. Algorithms of differential diagnostics of diseases accompanied by prolonged and chronic cough in children. Pediatriya. Zhurnal imeni G.N. Speranskogo. 2018;97(2):8-18. (In Russ.)

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3. Advantages and disadvantages of combined mucolytic therapy in children;Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics);2020-01-16

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