Anti-inflammatory treatment of conjunctivitis against the background of shigellosis and chlamydia: clinical observations

Abstract

Conjunctivitis accounts for about a third of all ocular pathology in clinical ophthalmology and is the most common inflammatory lesion of the eyes. This nosology can be both infectious and non-infectious in nature. The protection of the visual organ from exogenous and endogenous antigens is carried out with the help of highly specialized lymphoid tissue associated with the eye, which belongs to the peripheral organs of the immune system. The main task of the lymphoid tissue of the eye surface, which includes the conjunctiva, is to maintain a balance between the inflammatory immune response and tolerance to non-pathogenic factors, preventing the development of a permanent inflammatory reaction. Chronic conjunctivitis develops in patients with increased sensitization to a particular antigen. The article presents various aspects of pathogenesis, clinical picture, modern diagnostic methods, as well as management tactics for patients with chronic conjunctivitis of endogenous etiology, which developed against the background of systemic infectious diseases: shigellosis and chlamydia. The clinical efficacy of a combination of antibacterial drugs using the nonsteroidal anti-inflammatory drug bromfenac has been demonstrated. With a prolonged course of chronic conjunctivitis and the absence of a positive response to local therapy, additional examination is necessary to identify possible endogenous etiological factors.