Clinical case of disseminated histoplasmosis in a kidney graft recipient

Author:

Titova P. G.1ORCID,Shmarina N. V.2ORCID,Lazareva K. E.3ORCID,Nefedova G. A.1ORCID,Dmitriev I. V.2ORCID,Balkarov A. G.4ORCID

Affiliation:

1. N.V. Sklifosovsky Research Institute for Emergency Medicine

2. N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University

3. N.V. Sklifosovsky Research Institute for Emergency Medicine; Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of Medicine

4. N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University; Research Institute for Healthcare Organization and Medical Management

Abstract

Introduction. Histoplasmosis is not an endemic form of fungal infection in Russia; its sporadic cases are mainly associated with the import of the fungus from endemic countries. We consider it necessary to demonstrate a rare case of the disseminated histoplasmosis development in a kidney transplant recipient.Objective. Demonstration of a case of the disseminated histoplasmosis development in a kidney transplant recipient.Results. The clinical manifestations of the disease were described; the affected organs were macroscopically and histologically studied, which made it possible to diagnose disseminated histoplasmosis.Conclusions. This case prompts being on alert to potential occurrence of fungal infections, including non-endemic ones, in patients receiving immunosuppressive therapy.

Publisher

IPO Association of Transplantologists

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