Consequences of the variability of the CovRS and RopB regulators among Streptococcus pyogenes causing human infections
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep12057.pdf
Reference44 articles.
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2. Engleberg, N. C., Heath, A., Miller, A., Rivera, C. & DiRita, V. J. Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection. J. Infect. Dis. 183, 1043–1054 (2001).
3. Sumby, P., Whitney, A. R., Graviss, E. A., DeLeo, F. R. & Musser, J. M. Genome-wide analysis of group A streptococci reveals a mutation that modulates global phenotype and disease specificity. PLoS Pathog. 2, e5 (2006).
4. Churchward, G. The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci. Mol. Microbiol. 64, 34–41 (2007).
5. Graham, M. R. et al. Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc. Natl. Acad. Sci. USA 99, 13855–13860 (2002).
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