The Connectivity Map: a new tool for biomedical research
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/nrc2044.pdf
Reference63 articles.
1. Vane, J. R. & Botting, R. M. The mechanism of action of aspirin. Thromb. Res. 110, 255–258 (2003).
2. Druker, B. J. et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344, 1031–1037 (2001).
3. Black, J. Drugs from emasculated hormones: the principle of syntopic antagonism. Science 245, 486–493 (1989).
4. Lamb, J. et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929–1935 (2006).
5. Hieronymus, H. et al. Gene expression signature-based chemical genomic prediction identifies novel class of HSP90 pathway modulators. Cancer Cell 10, 321–330 (2006).
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