PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells-Reference-Cited by-同舟云学术

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PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

Published:2012-05-16 Issue:7404 Volume:486 Page:549-553
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Cipolletta Daniela,Feuerer Markus,Li Amy,Kamei Nozomu,Lee Jongsoon,Shoelson Steven E.,Benoist Christophe,Mathis Diane

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature11132.pdf

Reference23 articles.

1. Osborn, O. & Olefsky, J. M. The cellular and signaling networks linking the immune system and metabolism in disease. Nature Med. 18, 363–374 (2012)

2. Feuerer, M. et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nature Med. 15, 930–939 (2009)

3. Winer, S. et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nature Med. 15, 921–929 (2009)

4. Ilan, Y. et al. Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice. Proc. Natl Acad. Sci. USA 107, 9765–9770 (2010)

5. Tontonoz, P. & Spiegelman, B. M. Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289–312 (2008)

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