PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin-Reference-Cited by-同舟云学术

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

Published:2011-01-18 Issue:1 Volume:2 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Frateschi Simona,Camerer Eric,Crisante Giovanna,Rieser Sarah,Membrez Mathieu,Charles Roch-Philippe,Beermann Friedrich,Stehle Jean-Christophe,Breiden Bernadette,Sandhoff Konrad,Rotman Samuel,Haftek Marek,Wilson Anne,Ryser Stephan,Steinhoff Martin,Coughlin Shaun R.,Hummler Edith

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms1162.pdf

Reference59 articles.

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2. Proksch, E., Brandner, J. M. & Jensen, J. M. The skin: an indispensable barrier. Exp. Dermatol. 17, 1063–1072 (2008).

3. Huber, M. et al. Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Science 267, 525–528 (1995).

4. Basel-Vanagaite, L. et al. Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase. Am. J. Hum. Genet. 80, 467–477 (2007).

5. Descargues, P. et al. Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat. Genet. 37, 56–65 (2005).

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