Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein-Reference-Cited by-同舟云学术

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Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein

Published:2003-10-26 Issue:11 Volume:9 Page:1423-1427
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Amsellem Sophie,Pflumio Françoise,Bardinet Dominique,Izac Brigitte,Charneau Pierre,Romeo Paul-Henri,Dubart-Kupperschmitt Anne,Fichelson Serge

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm953.pdf

Reference24 articles.

1. Weissman, I.L., Anderson, D.J. & Gage, F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu. Rev. Cell. Dev. Biol. 17, 387– 403 (2001).

2. Sauvageau, G. et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 9, 1753– 1765 (1995).

3. Antonchuk, J., Sauvageau, G. & Humphries, R.K. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109, 39– 45 (2002).

4. Thorsteinsdottir, U., Sauvageau, G. & Humphries, R.K. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size. Blood 94, 2605– 2612 (1999).

5. Derossi, D. et al. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J. Biol. Chem. 271, 18188– 18193 (1996).

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