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Randomised phase II study of S-1/cisplatin plus TSU-68 vs S-1/cisplatin in patients with advanced gastric cancer

  • Published:2013-09-17 Issue:8 Volume:109 Page:2079-2086
  • ISSN:0007-0920
  • Container-title:British Journal of Cancer
  • language:en
  • Short-container-title:Br J Cancer

Author:

Koizumi W,Yamaguchi K,Hosaka H,Takinishi Y,Nakayama N,Hara T,Muro K,Baba H,Sasaki Y,Nishina T,Fuse N,Esaki T,Takagi M,Gotoh M,Sasaki T

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference22 articles.

1. Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Ruschoff J, Kang YK (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376: 687–697.

2. Boku N, Yamamoto S, Fukuda H, Shirao K, Doi T, Sawaki A, Koizumi W, Saito H, Yamaguchi K, Takiuchi H, Nasu J, Ohtsu A Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group (2009) Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study. Lancet Oncol 10: 1063–1069.

3. Fuchs CS, Tomasek J, Cho JY, Dumitru F, Passalacqua R, Goswami C, Safran H, Dos Santos LV, Aprile G, Ferry DR, Melichar B, Tehfe M, Topuzov E, Tabernero J, Zalcberg JR, Chau I, Koshiji M, Hsu Y, Schwartz JD, Ajani JA (2013) REGARD: A phase III, randomized, double-blinded trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing combination therapy. J Clin Oncol 31 (4_suppl): LBA5.

4. Inaba F, Kanai F, Aramaki T, Yamamoto T, Tanaka T, Yamakado K, Kaneko S, Kudo M, Imanaka K, Kora S, Nishida N, Kawai N, Seki H, Matsui O, Arioka H, Arai Y (2013) A randomised phase II study of TSU-68 in patients with hepatocellular carcinoma treated by transarterial chemoembolization. Eur J Cancer 49: 2832–2840.

5. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61: 69–90.

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