P53 conformational switching for selectivity may reveal a general solution for specific DNA binding
Author:
Affiliation:
1. Department of Molecular Biology, Skaggs Institute for Chemical Biology, The Scripps Research Institute; La Jolla CA USA
2. Life Sciences Division, Bioenergy and Structural Biology, Lawrence Berkeley National Laboratory; Berkeley CA USA
Publisher
Wiley
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience
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3. Structural biology of the tumor suppressor p53;Joerger;Annu Rev Biochem,2008
4. The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O6-alkylguanine adducts in E. coli;Mazon;DNA Repair,2009
5. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination;Mol;Nature,2000
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1. Recognition of Local DNA Structures by p53 Protein;International Journal of Molecular Sciences;2017-02-10
2. Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein;Journal of Molecular Biology;2014-02
3. A magnetic electrochemical immunosensor for the detection of phosphorylated p53 based on enzyme functionalized carbon nanospheres with signal amplification;RSC Adv.;2014
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5. Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element;Molecular Cancer Research;2011-09-20
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