Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila-Reference-Cited by-同舟云学术

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Published:2011-09 Issue:7365 Volume:477 Page:482-485
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Burnett Camilla,Valentini Sara,Cabreiro Filipe,Goss Martin,Somogyvári Milán,Piper Matthew D.,Hoddinott Matthew,Sutphin George L.,Leko Vid,McElwee Joshua J.,Vazquez-Manrique Rafael P.,Orfila Anne-Marie,Ackerman Daniel,Au Catherine,Vinti Giovanna,Riesen Michèle,Howard Ken,Neri Christian,Bedalov Antonio,Kaeberlein Matt,Sőti Csaba,Partridge Linda,Gems David

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature10296.pdf

Reference36 articles.

1. Tissenbaum, H. A. & Guarente, L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410, 227–230 (2001)

2. Viswanathan, M., Kim, S. K., Berdichevsky, A. & Guarente, L. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev. Cell 9, 605–615 (2005)

3. Rogina, B. & Helfand, S. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl Acad. Sci. USA 101, 15998–16003 (2004)

4. Partridge, L. & Gems, D. Benchmarks for ageing studies. Nature 450, 165–167 (2007)

5. Kaeberlein, M., McVey, M. & Guarente, L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13, 2570–2580 (1999)

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