Reductive carboxylation supports growth in tumour cells with defective mitochondria-Reference-Cited by-同舟云学术

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Published:2011-11-20 Issue:7381 Volume:481 Page:385-388
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Mullen Andrew R.,Wheaton William W.,Jin Eunsook S.,Chen Pei-Hsuan,Sullivan Lucas B.,Cheng Tzuling,Yang Youfeng,Linehan W. Marston,Chandel Navdeep S.,DeBerardinis Ralph J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature10642.pdf

Reference26 articles.

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3. DeBerardinis, R. J. et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc. Natl Acad. Sci. USA 104, 19345–19350 (2007)

4. Linehan, W. M., Srinivasan, R. & Schmidt, L. S. The genetic basis of kidney cancer: a metabolic disease. Nature Rev. Urol. 7, 277–285 (2010)

5. Baysal, B. E. et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 287, 848–851 (2000)

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