Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/nbt.4180.pdf
Reference40 articles.
1. Cheong, J.E. & Sun, L. Targeting the IDO1–TDO2–KYN–AHR pathway for cancer immunotherapy—challenges and opportunities. Trends Pharmacol. Sci. 39, 307–325 (2018).
2. Prendergast, G.C., Malachowski, W.P., DuHadaway, J.B. & Muller, A.J. Discovery of IDO1 inhibitors: from bench to bedside. Cancer Res. 77, 6795–6811 (2017).
3. Munn, D.H. & Mellor, A.L. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J. Clin. Invest. 117, 1147–1154 (2007).
4. Badawy, A.A.-B., Namboodiri, A.M.A. & Moffett, J.R. The end of the road for the tryptophan depletion concept in pregnancy and infection. Clin. Sci. (Lond.) 130, 1327–1333 (2016).
5. Sonner, J.K. et al. The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas. OncoImmunology 5, e1240858 (2016).
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