Caspase activation precedes and leads to tangles-Reference-Cited by-同舟云学术

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Caspase activation precedes and leads to tangles

Published:2010-03-31 Issue:7292 Volume:464 Page:1201-1204
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

de Calignon Alix,Fox Leora M.,Pitstick Rose,Carlson George A.,Bacskai Brian J.,Spires-Jones Tara L.,Hyman Bradley T.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature08890.pdf

Reference30 articles.

1. Ramsden, M. et al. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L). J. Neurosci. 25, 10637–10647 (2005)

2. Gómez-Isla, T. et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer’s disease. Ann. Neurol. 41, 17–24 (1997)

3. Augustinack, J. C., Schneider, A., Mandelkow, E. M. & Hyman, B. T. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer’s disease. Acta Neuropathol. 103, 26–35 (2002)

4. Ramalho, R. M. et al. Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol. Med. 14, 309–317 (2008)

5. Guo, H. et al. Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer’s disease. Am. J. Pathol. 165, 523–531 (2004)

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