Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved‐like phenotype

Author:

Ballarò Costanza1,Ceccarelli Sara1,Tiveron Cecilia2,Tatangelo Laura2,Salvatore Anna Maria3,Segatto Oreste2,Alemà Stefano1

Affiliation:

1. Istituto di Biologia Cellulare CNR, Via Ramarini, 32 00016 Monterotondo Italy

2. Istituto Regina Elena and Transgenic Mice Service Center Via Delle Messi d'Oro, 156 00158 Rome Italy

3. Istituto di Neurobiologia e Medicina Molecolare CNR, Via Fosso del Fiorano 64‐00143 Rome Italy

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Reference22 articles.

1. Activated extracellular signal‐regulated kinases: association with epidermal growth factor receptor/transforming growth factor α expression in head and neck squamous carcinoma and inhibition by anti‐epidermal growth factor receptor treatments;Albanell J;Cancer Res,2001

2. Feedback inhibition by RALT controls signal output by the ErbB network

3. Tyrosine Phosphorylation and Src Family Kinases Control Keratinocyte Cell–Cell Adhesion

4. Endocytosis and Signaling

5. A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control

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