Mdm2 targets the p53 transcription cofactor JMY for degradation
Author:
Affiliation:
1. Laboratory of Cancer Biology, Division of Medical Sciences, John Radcliffe Hospital, University of Oxford Oxford OX3 9DU UK
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1038/sj.embor.7400855
Reference26 articles.
1. p53-Mdm2--the affair that never ends
2. E3 ubiquitin ligases
3. Stress Signals Utilize Multiple Pathways To Stabilize p53
4. mdm2 expression is induced by wild type p53 activity.
5. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
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