Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion-Reference-Cited by-同舟云学术

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Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion

Published:2021-09-07 Issue: Volume: Page:
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Wei Yuan-yuan,Ma Yan,Yao Song-yu,Kong Ling-hui,Liu Xiao,Chai Jing-rui,Chen Jing,Li Wei,Wang Yu-jun,Shao Li-ming,Liu Jing-gen

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-021-00761-x.pdf

Reference49 articles.

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2. Rodriguez RE. Morphine and microRNA activity: is there a relation with addiction? Front Genet. 2012;3:223.

3. Abushanab D, Alsoukhni O, AbouNahia F, Al-Badriyeh D. Clinical and economic analysis of morphine versus fentanyl in managing ventilated neonates with respiratory distress syndrome in the intensive care setting. Clin Ther. 2019;41:714–27 e8.

4. Kiyatkin EA. Respiratory depression and brain hypoxia induced by opioid drugs: Morphine, oxycodone, heroin, and fentanyl. Neuropharmacology. 2019;151:219–26.

5. Chey WD, Webster L, Sostek M, Lappalainen J, Barker PN, Tack J. Naloxegol for opioid-induced constipation in patients with noncancer pain. N Engl J Med. 2014;370:2387–96.

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1. Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect;Journal of Medicinal Chemistry;2024-04-22

2. Endogenous opiates and behavior: 2022;Peptides;2023-11

3. SLL-627 Is a Highly Selective and Potent κ Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity;Journal of Medicinal Chemistry;2022-07-28

4. The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies;Frontiers in Pharmacology;2022-06-20

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