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GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi

  • Published:2017-08-15 Issue:6 Volume:117 Page:884-887
  • ISSN:0007-0920
  • Container-title:British Journal of Cancer
  • language:en
  • Short-container-title:Br J Cancer

Author:

Vader M J C,Madigan M C,Versluis M,Suleiman H M,Gezgin G,Gruis N A,Out-Luiting J J,Bergman W,Verdijk R M,Jager M J,van der Velden P A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference14 articles.

1. Baderca F, Solovan C, Boghian L (2013) Epidemiological and morphological data of ocular melanocytic lesions. Rom J Morphol Embryol 54 (1): 77–83.

2. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA (2002) Mutations of the BRAF gene in human cancer. Nature 417 (6892): 949–954.

3. Mouti MA, Dee C, Coupland SE, Hurlstone AF (2016) Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafish. Oncotarget 7 (26): 39654–39670.

4. Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA (2006) Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc Natl Acad Sci USA 103 (33): 12405–12410.

5. Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, Moses TY, Hostetter G, Wagner U, Kakareka J, Salem G, Pohida T, Heenan P, Duray P, Kallioniemi O, Hayward NK, Trent JM, Meltzer PS (2003) High frequency of BRAF mutations in nevi. Nat Genet 33 (1): 19–20.
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