Signalling through C-type lectin receptors: shaping immune responses
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri2569.pdf
Reference106 articles.
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3. Gringhuis, S. I. et al. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-κB. Immunity 26, 605–616 (2007). This study identifies the RAF1 signalling pathway as being involved in the modulation of immune responses by DC-SIGN.
4. Gringhuis, S. I. et al. Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and SYK. Nature Immunol. 10, 203–213 (2009). This study shows that T H cell differentiation is tailored to the pathogen through the integration of two signalling pathways induced by dectin 1; one through RAF1 and one through SYK.
5. Rogers, N. C. et al. SYK-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22, 507–517 (2005). This is the first study to show that SYK is essential for dectin 1-induced immunity.
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