Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (−) and ER (+) Breast Cancer-Reference-Cited by-同舟云学术

Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (−) and ER (+) Breast Cancer

Published:2013 Issue: Volume:2 Page:e121
ISSN:2162-2531
Container-title:Molecular Therapy - Nucleic Acids
language:en
Short-container-title:Molecular Therapy - Nucleic Acids

Author:

Tekedereli Ibrahim,Alpay S Neslihan,Akar Ugur,Yuca Erkan,Ayugo-Rodriguez Cristian,Han He-Dong,Sood Anil K,Lopez-Berestein Gabriel,Ozpolat Bulent

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference48 articles.

1. The BCL-2 protein family: opposing activities that mediate cell death;Youle;Nat Rev Mol Cell Biol,2008

2. Bcl-2 family proteins and cancer;Yip;Oncogene,2008

3. BCL-2 gene family and the regulation of programmed cell death;Korsmeyer;Cancer Res,1999

4. Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy;Buchholz;Cancer J,2003

5. Targeting the Bcl-2;Patel;Curr Opin Oncol,2009

Cited by 84 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis;Cell Death Discovery;2024-04-22

2. Characterization of the modulatory effect of zeaxanthin isolated from maize kernels on cellular signaling pathways associated with hyperglycemia-induced HepG2 cell proliferation;PharmaNutrition;2024-03

3. Polyamidoamine-Carbon Nanodot Conjugates with Bioreducible Building Blocks: Smart Theranostic Platforms for Targeted siRNA Delivery;Biomacromolecules;2024-01-05

4. Engineered extracellular vesicles: A new approach for targeted therapy of tumors and overcoming drug resistance;Cancer Communications;2023-12-28

5. Liposomal nanocarriers containing siRNA as small molecule-based drugs to overcome cancer drug resistance;Nanomedicine;2023-11-15