Transcription as a source of genome instability
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg3152.pdf
Reference125 articles.
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2. Herman, R. K. & Dworkin, N. B. Effect of gene induction on the rate of mutagenesis by ICR-191 in Escherichia coli. J. Bacteriol. 106, 543–550 (1971).
3. Datta, A. & Jinks-Robertson, S. Association of increased spontaneous mutation rates with high levels of transcription in yeast. Science 268, 1616–1619 (1995). This work, using budding yeast as a model system, was the first demonstration of transcription-associated mutagenesis in eukaryotic cells.
4. Saxowsky, T. T. & Doetsch, P. W. RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis? Chem. Rev. 106, 474–488 (2006).
5. Keil, R. L. & Roeder, G. S. Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S. cerevisiae. Cell 39, 377–386 (1984).
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