Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/nbt.4166.pdf
Reference37 articles.
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3. Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910–918 (2013).
4. Yao, X. et al. Homology-mediated end joining-based targeted integration using CRISPR/Cas9. Cell Res. 27, 801–814 (2017).
5. Cohen, J. 'Any idiot can do it': genome editor CRISPR could put mutant mice in everyone's reach. Science https://doi.org/10.1126/science.aal0334 (2016).
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