Author:
Goldstein David B.,Tate Sarah K.,Sisodiya Sanjay M.
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Reference54 articles.
1. Weber, W. W. Pharmacogenetics (Oxford Univ. Press, New York and Oxford, 1997).
2. Motulsky, A. G. Drug reactions, enzymes, and biochemical genetics. J. Am. Med. Assoc. 165, 835–837 (1957). This paper was the first to make explicit the hypothesis that variation among individuals in drug response might be owing to subtle genetic differences with little or no obvious phenotypes except in response to the relevant drug. This perspective contributed directly to the development of pharmacogenetics as a distinct discipline.
3. Mahgoub, A., Idle, J. R., Dring, L. G., Lancaster, R. & Smith, R. L. Polymorphic hydroxylation of debrisoquine in man. Lancet 2, 584–586 (1977).
4. Nebert, D. W. & Dieter, M. Z. The evolution of drug metabolism. Pharmacology 61, 124–135 (2000).
5. El-Bacha, R. S. & Minn, A. Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain. Cell. Mol. Biol. 45, 15–23 (1999).
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